Here is a guide on how to get all achievements.
Gameplay/Campaign [Unmissable-Story]
Calico
Visit Calico for the first time
Ticks & Leeches
Defeat The Parasiter
Adapt or Die
Defeat the Bruch
Drop of Blood
Defeat William Rentier
Ancient Blood
Defeat Felicity D’Abano
Gameplay/Campaign
Novice
Beat the game on Novice difficulty or higher
Adept
Beat the game on Normal difficulty or higher
Expert
Beat the game on Hard difficulty or higher
Weird West Superhero
Beat the game on Evil difficulty————————————————-
Minor Deity
Defeat The Parasiter on Evil difficulty
Bio Friendly
Defeat The Parasiter without killing any of the minions
Weren’t You Listening?
Defeat the Bruch on Evil difficulty
Bleed You Out
Defeat the Bruch without letting it heal
Then You Died
Defeat William Rentier on Evil difficulty
Father’s Day
Defeat William Rentier in less than 6 minutes
Best the Beast
Defeat Felicity D’Abano without using the HP dispenser
Kills [Easy]
Pointless Violence
Perform 15 finishers
In the Feels
Hit 45 weakspots
Mighty Mitten
Kill 10 enemies in a row using only Gauntlet after obtaining the Revolver
E-Rodeo
Kill 20 enemies using the E-Combo
Chewing Volts
Use 15 Energy charges
Monsterball
Cannonball enemies 50 times
Sever Forever
Tear off 100 limbs from enemies
Slam Champion
Slam enemies 100 times
Pew Pew Die
Kill at least 30 enemies with each electrically-augmented firearm
Spark of Hope
Activate the Supercharged Mode for the first time
Other
Boys’n’Toys
Have all Weapon Upgrades activated at the same time
Sanguis Aeternus
All Trophies unlocked. The Weird West is a better place now.
Collectables [Complete]
**You are able to replay levels from the pause menu, under Lore and it will not effect your current progress. You are also able to leave at any time and the collectables will be saved.
Chest Nuts
Pick up all cash on all missions
Field Agent
Find all hidden perks
Level/Chp 01 – “The Questionable Cargo” – All Collectables
Level/Chp 02 – “The Raid” – All Collectables
Level/Chp 04 – “From Dusk Till Dawn” – All Collectables
Level/Chp 05 – “The Devil’s Pass” – All Collectables
Level/Chp 06 – “Remote RI Outpost” – All Collectables
Level/Chp 07 – “Smoke and Mirrors” – All Collectables
Level/Chp 08 – “Pharmakon” – All Collectables
Level/Chp 09 – “Where Oil tastes like Blood” – All Collectables
Level/Chp 10 – “Bats in the Belfry” – All Collectables
Level/Chp 11 – “A Man of the People” – All Collectables
Level/Chp 12 – “Lightening in a Bottle” – All Collectables
Level/Chp 13 – “Old Friends” – All Collectables
Level/Chp 14 – “A Son’s Duty” – All Collectables
Level/Chp 15 – “The Heist” – All Collectables
Level/Chp 16 – “The Grand Finale” – All Collectables
By Raxrr
